Which route is NOT available for the administration of acetaminophen?

Acetaminophen, also known as paracetamol, is commonly administered through several routes including oral, rectal, and intravenous. The oral route is frequently used for its convenience and effectiveness, making it one of the most popular methods for taking this medication. The rectal route is beneficial particularly for patients who may be unable to take medications by mouth. Intravenous administration is often utilized in hospital settings where rapid pain relief or fever reduction is required, allowing for precise dosing and immediate effects.

In contrast, administration by the intramuscular route is not standard for acetaminophen. This is primarily because acetaminophen is effectively absorbed through the other three routes, and there has been limited use of the intramuscular route in practice for this medication. Additionally, the potential for pain and tissue damage at the injection site makes this route less desirable compared to the alternatives available. Therefore, recognizing the standard routes for acetaminophen administration helps in understanding how to safely and effectively manage pain and fever in clinical practice.